Decitabine FDA Link

An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

Also Known As:

2'-Deoxy-5-azacytidine; 5-Aza-2'-deoxycytidine; 5-AzadC; 5-Azadeoxycytidine; 5-Deoxyazacytidine; 5AzadC; AzadC Compound; Dacogen; Decitabine Mesylate; NSC 127716; NSC-127716; 2' Deoxy 5 azacytidine; 5 Aza 2' deoxycytidine; 5 Azadeoxycytidine; 5 Deoxyazacytidine; Compound, AzadC; Mesylate, Decitabine; NSC127716

Organic Chemicals: 140
- Aza Compounds: 3
  - Azacitidine: 2162
    - Decitabine: 2499
Heterocyclic Compounds: 207
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 521
    - Pyrimidine Nucleosides: 50
      - Cytidine: 548
        Azacitidine: 2162
        Decitabine: 2499
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6937
  - Pyrimidine Nucleosides: 50
    - Cytidine: 548
      - Azacitidine: 2162
        Decitabine: 2499
  - Ribonucleosides: 49
    - Cytidine: 548
      - Azacitidine: 2162
        Decitabine: 2499

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Disease

Drug/Important Bio-Agent (IBA)